UEMS Medical Specialty

Geriatrics & Longevity Medicine — Page 2

Dossiers covering senolytic compounds, NAD⁺ precursor supplementation, cellular senescence, and evidence-based longevity medicine formulations.

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dossiers

Cellular Longevity & Senolytics

Synergistic Modulation of Cellular Senescence Biomarkers by Target-Specific Nutraceutical Matrices

Developing a nutraceutical matrix that precisely modulates senescence-related biomarkers requires integrating senolytic activity, SASP suppression, and mitochondrial restoration within a single formulation while ensuring in vitro reproducibility and scalability.

SenotherapeuticsCellular SenescenceNADInflammation

Cellular Longevity & Senolytics

Comparative Pharmacokinetics and Cellular Bioaccessibility of Senolytic Agents: Impact of Polymeric-Matrix Encapsulation

Orally administered senolytic compounds often suffer from poor pharmacokinetics, including low and variable bioavailability, rapid metabolism, pH-dependent dissolution, and limited cellular bioaccessibility.

SenotherapeuticsNanoparticlesDrug CompoundingBiological Availability

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